NAD+ VITAL ENERGY COMPLEX
For skin that’s running on less energy than it deserves — because vitality is biological, not just a feeling.
AM Ritual · Skin Longevity Protocol™ — Step 04 · Taken with breakfast
You have felt it. The afternoon energy dip. Skin that looks tired no matter how well you slept or how good your serums are.
That is because the fuel your cells run on, called NAD+, falls by roughly half by your late thirties. This is the step that refills it, from the inside.
Skincare works on the surface. This works underneath it.
- Steadier energy through the day Fewer afternoon crashes, more of the get-up-and-go you remember.
- The lit-from-within look serums can’t fake Radiance that starts at the cellular level, not the surface.
- The inside half of your routine The part topicals were never able to reach.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
“No topical serum can compensate for a cellular energy deficit. This is the layer that makes everything else work harder — from the inside.”
— Dr. Gilbert Maleke, MD · Founder, VitaalSkin
500mg
NAD+ per serving
~50%
Decline by your late 30s
3-in-1
NAD+, Quercetin & Resveratrol
The layer no topical can replace
You can do everything right on the surface. The serums, the SPF, the consistency. And still catch your reflection looking tired in a way no cream seems to touch.
Here is why. Your skin is powered by your cells, and your cells run on a molecule called NAD+. By your late thirties it has fallen by roughly half, and no topical can reach in and refill it.
That is the half of aging that happens underneath the surface. This is the step that finally addresses it, from the inside out.
How it feels
Less about what it does.
More about how you feel doing it.
Energy that lasts
The quiet steadiness of getting through your day without the crash you had learned to expect.
Radiance from within
The look of being genuinely well, the kind of glow that no highlighter or serum can imitate.
Doing the whole job
The peace of mind of finally treating the inside, not just the surface. Both halves, covered.
What your skin shows, and when
Honest timelines.
Real biology takes weeks, not hours.
We will never promise overnight transformation. Here is what most people notice, in the order they tend to notice it, taking it consistently every morning.
Weeks 1–2
Foundation
NAD+ levels begin to replenish. This stage is quiet groundwork, not fireworks. Consistency is everything here.
Weeks 3–4
Energy
Many people notice steadier daily energy and fewer of those familiar afternoon dips.
Weeks 6–8
Glow
Skin often looks more rested and radiant as cellular repair is better fuelled from within.
Weeks 12+
Vitality
The compounding benefit of consistently supported cellular energy, the long game of longevity.
These are typical observations, not guarantees. Skin biology varies from person to person. The one variable in your control is consistency.
Proof & formulation
A 3-in-1 cellular longevity stack.
Each ingredient was chosen for a specific role in the NAD+ pathway, not as a generic antioxidant blend. Refill the fuel, protect it from breakdown, and calm what works against your repair.
Why a physician built the pathway, not just NAD+
In plain terms: taking NAD+ on its own is not enough. An enzyme called CD38 breaks it down, and inflammation quietly works against your repair. So this stack does three things at once: it refills NAD+, slows its breakdown, and calms the signaling that gets in the way.
That is why it is Step 04. It is the inside layer, the part of longevity no cream can reach.
“No topical serum can compensate for a cellular energy deficit. This is the layer that makes everything else work harder — from the inside.”
Dr. Gilbert Maleke, MD · Founder, VitaalSkin
NAD+ (Nicotinamide Adenine Dinucleotide)
500 mg · the cellular fuel
Essential coenzyme for mitochondrial energy production, sirtuin activation, DNA repair, and collagen gene expression.
Quercetin Dihydrate
250 mg · Sophora japonica · the protector
A CD38 inhibitor that slows NAD+ breakdown, increasing how much of the NAD+ you take actually reaches your cells.
Resveratrol (98%)
150 mg · Japanese Knotweed root · the longevity switch
A high-purity SIRT1 activator that supports reduction of the inflammatory signaling working against collagen and skin repair.
Veggie Capsule (HPMC)
The clean delivery
Plant-derived and vegan, with no animal gelatin, consistent with the protocol's formulation standards.
Full supplement facts
Active per serving: NAD+ (500 mg), Quercetin Dihydrate Extract, Sophora japonica whole flower bud (250 mg), Japanese Knotweed Extract 98% Resveratrol, Polygonum cuspidatum root (150 mg). Other ingredients: HPMC (vegetable capsule), Microcrystalline Cellulose, Brown Rice Flour, Olive Oil, Silicon Dioxide, Magnesium Stearate. Do not exceed the recommended dose. Store in a cool, dry place.
How to take it
Two capsules. Every morning. With breakfast.
Take two capsules each morning with food and a full glass of water. Food helps absorption and keeps it gentle. It works from the inside while your topical steps work on the surface.
Take with food
Two capsules each morning with a meal and at least 6 oz of water. Food supports absorption and comfort.
Pair with the topical steps
NAD+ works from within while your serums work on the surface. Together they cover both halves of skin longevity.
Morning Protocol
- PDRN Serum (topical)
- HydraBarrier HA Cream
- NAD+ (2 capsules with food)
- KSM-66 (1 capsule, optional AM)
- SPF 30+ (your favorite)
Dosing Guidelines
- 2capsules per day
- 6ozwater minimum
- AMTake with food
- 30d60 capsules = 30-day supply
If you are pregnant, nursing, taking medication, or have a known medical condition, consult your physician before use. Keep out of reach of children.
Why VitaalSkin
Most brands sell you products.
We built you a system.
This supplement is not a standalone hero. It is Step 04 of one connected method, the literal inside layer of an inside-out strategy, where every ingredient was chosen for its role, never for the marketing.
A system, not a shelf
Five steps designed to work together in sequence. No random layering, no competing formulas.
Inside-out by design
Topical and internal, because skin longevity is a whole-body process, not a surface one.
Vegan and plant-derived
Every active is vegan and of plant origin. Clean formulas, clinically dosed, nothing ornamental.
Formulated by a physician
Built by Dr. Gilbert Maleke on 30 years in preventive medicine, not by a trend team.

Where this began
Prevention, not correction.
For 30 years, Dr. Gilbert Maleke watched patients invest in every part of their health, then treat their skin only after the damage showed. He built VitaalSkin to change the order of things. To support skin before it asks for help, the way the rest of preventive medicine already does.
“Skin does not exist outside the body. It deserves the same preventive thinking we already apply to the rest of our health.”
Dr. Gilbert Maleke, MDPhysician · 30 years in preventive medicine · Founder
Discover the brand →Real results, real words
We do not invent reviews.
Longevity takes time, so we let real results accumulate honestly.
I like routines that feel built for the long game, and this is exactly that. It makes the whole system feel more grounded and elevated.
Hannac C.Verified buyer
This is the kind of addition that makes sense when you want a real long-term routine. I like that it feels supportive instead of trendy.
Lauren P.Verified buyer
I didn’t expect a supplement step to feel this important, but it really does. It makes the whole protocol feel more complete and intentional.
JessicaVerified buyer
Your questions, answered
NAD+ Vital Energy Complex FAQ
What does the NAD+ Vital Energy Complex actually do?
It supports the cellular energy pathway your skin and body run on. NAD+ fuels mitochondrial energy, sirtuin activity, and DNA repair. Quercetin helps protect those NAD+ levels, and resveratrol supports a calmer inflammatory environment. Together they support cellular energy and healthy aging from the inside.
How long before I notice anything?
The first weeks are quiet groundwork as levels replenish. Many people notice steadier daily energy around weeks 3 to 4, a more rested, radiant look by weeks 6 to 8, and the fuller vitality benefit compounding from week 12. Like everything in longevity, consistency is what pays off.
Can I take it with my other supplements or medications?
It is generally well tolerated alongside common supplements. That said, if you are pregnant, nursing, taking prescription medication, or managing a medical condition, talk to your physician before starting. We would always rather you check first.
Why take a supplement if I already use the serums?
Because topicals can only reach the surface. NAD+ declines inside your cells, where no cream can go. This is the inside half of skin longevity, and pairing it with the topical steps is what makes the VitaalSkin approach genuinely inside-out.
Is it safe for long-term, daily use?
It is formulated for daily use as part of a long-term longevity routine, at clinically considered doses, in FDA-registered, GMP-certified facilities. Do not exceed the recommended two capsules per day. As with any supplement, consult your physician if you have specific health concerns.
Is it vegan, and what is in the capsule?
Yes. It is vegan and vegetarian, gluten-free, non-GMO, and uses a plant-derived HPMC capsule with no animal gelatin. Full supplement facts are listed in the formulation section above.
When and how should I take it?
Two capsules every morning with breakfast and at least 6 oz of water. Taking it with food supports absorption and keeps it comfortable on the stomach. One bottle of 60 capsules is a 30-day supply.
What is your return policy?
Every order is backed by a 30-day guarantee. Give it an honest try for the full window. If it is not right for you, contact us and we will make it right.
Where would you like to start?
This supplement is just Step 04. The inside layer.
Start small
NAD+ Vital Energy Complex
The inside layer, on its own. The simplest way to support the cellular energy no topical can reach.
Add the complex to cartBest value · save up to 30%
The full 5-step protocol
All five steps, working as one system. Topical and internal, the complete inside-out strategy Dr. Maleke designed. Save 10% one-time, or up to 30% on a monthly subscription.
Explore the protocol →These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Formulated and manufactured in the USA in FDA-registered, GMP-certified facilities.